Cell Therapy

Cell therapy is the introduction of selected, and sometimes engineered, cells into a patient to treat disease. For example, in immunotherapy, T cells capable of fighting cancer cells may be injected in order to treat the disease. The therapy may have wide applications as a cancer treatment, with the potential for cure in some patients.

Syncona has a world-leading cell therapy franchise developing products with the potential to treat patients across a range of diseases. We have established and built fully-integrated companies with best-in-class manufacturing capabilities and world-leading management teams across innovative areas of cell therapy including: CAR-T, Tumour Infiltrating Lymphocytes and T-Regulatory cells.

Autolus is a clinical-stage biopharmaceutical company developing next-generation programmed T cell therapies for the treatment of cancer
Achilles Therapeutics’ mission is to develop next-generation personalised therapies that harness the immune system to destroy cancer cells, with the potential to cure patients
Quell Therapeutics was founded in March 2019 with the aim of developing engineered T regulatory (Treg) cell therapies. Tregs are a subset of T cells with the potential to downregulate the immune system. Quell was founded by Syncona in partnership with six leading experts in the Treg field.

Syncona cell therapy portfolio

Syncona has proactively sought out nascent technology in the emerging cell therapy space to found, build and fund innovative companies focused on differentiated and next-generation cell therapies targeting poorly served diseases

T-regulatory cells

A subset of T cells with the potential to downregulate the immune system

Clonal neoantigens

Targeting tumour evolutionary principles to treat cancer

Engineered CAR-T cells

Highly active, controlled, T cell programming technologies

In each company we build our capabilities and technology to develop companies with industrial scale

  • Strategy
  • Commercial model
  • Leadership and Team
  • Delivery
  • Manufacturing
Developing a strategy and plan build a company which can take products to market