Sustainability

Committed to delivering a positive and sustainable impact

We are committed to managing our business in a sustainable way, investing responsibly and supporting our portfolio companies in making positive contributions to society by developing treatments for patients in areas of high unmet need.

We aim to have effective governance, a strong business culture, clear values, and positive engagement with the life sciences ecosystem through our engagement with industry and our support for charity.

We are actively engaged with our portfolio companies as they seek to build sustainable businesses.

“We are particularly proud of the impact that our companies can have on the lives of patients and their families, and the strong sense of purpose the team has to make a difference.”

Annabel Clark
Head of Corporate Affairs

Key pillars of our Sustainability Policy

We have engaged with our key stakeholders to understand the sustainability issues which are most material to the business. The outcome of the materiality assessment has been used to develop our Sustainability Policy which focuses on four key pillars.

  • Our social impact
  • Responsible investor and partner
  • Inspiring and empowering our people
  • Responsible and ethical business

Sustainability Report 2026

Our 2026 Sustainability Report outlines our Sustainability Policy, our approach to responsible investing and how we manage sustainability within the portfolio, and covers our activities for the 2025/6 financial year.

03.07.26 | pdf (8.12Mb)
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Our approach to reporting

Making and demonstrating a positive contribution to the UN Sustainable Development Goals (SDGs) is a key part of our approach to reporting on sustainability. The four key UN SDGs which our business is well-aligned with are:

Goal 3
Goal 3

Ensure healthy lives and promote well-being for all at all ages

Goal 8
Goal 8

Promote sustained, inclusive and sustainable economic growth, full and productive employment and decent work for all

Goal 9
Goal 9

Build resilient infrastructure, promote inclusive and sustainable industrialization and foster innovation

Goal 13
Goal 13

Take urgent action to combat climate change and its impacts

More about SDGs

Syncona is a signatory to the UN PRI

Syncona first became a signatory to the UN PRI in October 2021, underlining its commitment to reporting on its responsible investment approach. The PRI is recognised as the world's leading network for investors who are committed to integrating sustainability factors into their investment and stewardship practices. The Principles are aligned with the work being undertaken by Syncona as we engage with our portfolio companies on issues around sustainability in-line with our Responsible Investment Policy. Syncona submitted its first questionnaire to the PRI in FY2023/4 and remains committed to reporting to the PRI on an annual basis.

Reporting in-line with the recommendations of the Task Force on Climate-related Financial Disclosures

The Task Force on Climate-related Financial Disclosures (TCFD) is the principal global framework for assessing the risks and opportunities that are relevant to a company from climate change. Syncona is committed to incorporating climate risk analysis into its overall risk management framework and carried out a comprehensive climate scenario analysis in FY2021/22. Since this time, Syncona has re-visited this analysis on an annual basis to determine whether they remain accurate given the evolution of the portfolio. By taking this targeted approach, we are confident that Syncona’s exposure to climate-related risks is monitored effectively and that any changes in risk exposure can be identified and managed accordingly. While this year’s analysis did not identify any material climate-related risks to Syncona’s business, we recognise the potential for this to change and remain alert to the evolving nature of climate-related risks, ensuring we integrate them into our assessment processes.

Publishing out first net zero target

The Net Zero Asset Managers (NZAM) initiative is a growing collective of leading asset managers, including over 300 signatories holding nearly $59 trillion of AUM. The aim of the initiative is to bring together asset managers committed to supporting the goal of reaching net zero GHG emissions by 2050 or sooner, in line with the Paris Goals.

We underlined our commitment to limiting our portfolio’s environmental footprint by signing up to the NZAM initiative in 2023, and publishing our first NZAM target in 2024. This supports our overall aspiration to be net zero across our full value chain by 2050.