Autolus Therapeutics

Founded
2014
CEO
Christian Itin
Founder & CSO
Dr Martin Pule
Shareholding
10%
Stage
Commercial
Number of employees
c.650
Listing
NASDAQ (June 2018)
Clinical trials
8

Unless stated all financials at 31 March 2025.

Autolus website

Autolus is a CAR T cell therapy company, applying its extensive programming capabilities to develop advanced autologous T cell therapies that have the potential to deliver life-changing therapies to patients with cancer and autoimmune diseases.

Autolus is founded on advanced cell programming technology pioneered by Dr Martin Pule and was spun-out from University College London in 2014. Chimeric Antigen Receptor (CAR) T cell therapies have been shown to be effective in some haematological malignancies and may have wide applications as a cancer treatment, with the potential for cure in some patients.

A leader in T-cell programming and manufacturing technology, Autolus works in partnership with physicians and other healthcare providers to extract immune cells from patients, equip them with a receptor that targets the cancer cell and infuse them back into the patient in order to develop therapies which they believe will offer cancer patients substantial benefits over the existing standard of care.

 

The Autolus pipeline

Best ideas Pre-clinical Clinical Late Clinical BLA
  • Obe-cel - Adult ALL

  • Obe-cel - SLE

  • Obe-cel - B-NHL

  • Obe-cel – Paediatric B-ALL & B-NHL

  • Obe-cel - PCNSL

  • AUTO 1/22 - Paediatric ALL

  • AUTO4 - PTCL

  • AUTO6NG – Neuroblastoma

  • AUTO8 – Multiple myeloma