Resolution Therapeutics

Founded
2020
CEO
Amir Hefni
Founders
Prof. Stuart Forbes
Prof. John Campbell
Shareholding
83%
Stage
Clinical
Number of employees
57
Raised in Series B financing
£63.5m
Clinical trials
1

Unless stated all financials at 31 March 2025.

Resolution website

Resolution is developing macrophage cell therapies to repair inflammatory organ damage.

Syncona co-founded Resolution following a two year collaboration with researchers at the University of Edinburgh and the Scottish National Blood Transfusion Service.

Resolution is developing macrophage cell therapies to repair inflammatory organ damage, including treatment of end-stage chronic liver disease. Macrophages are cells of the innate immune system which orchestrate the body’s defence against infection and injury; the company is built upon more than a decade of work in the Founders’ laboratories characterising the role of macrophages in organ repair, including the liver, both in the pre-clinical and clinical settings.

Syncona team

Roel Bulthuis

Roel Bulthuis

Roel Bulthuis is Managing Partner, Head of Investments of Syncona Investment Management Limited Roel is currently a Managing Partner at Syncona, where he manages the investment team and utilises more than 20 years of life science venture capital, business development and investment banking experience to help Syncona deliver value through the investment cycle. He is a Board member of iOnctura and A…
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Position
Board observer
Qualification
MSc, MBA
Edward Hodgkin

Edward Hodgkin

Edward Hodgkin is a Managing Partner of Syncona Investment Management Ltd. He is currently the Chair of Mosaic Therapeutics and Slingshot Therapeutics, and a Board member of Resolution Therapeutics and OMass Therapeutics. He was also previously the first CEO and a board member of Autolus Therapeutics (NASDAQ:AUTL), and the former CEO of Resolution Therapeutics. Within the Syncona life science team…
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Position
Board member
Qualification
PhD
Gonzalo Garcia

Gonzalo Garcia

Gonzalo is a Principal of Syncona Investment Management Limited. Gonzalo is a Director on the Board of Yellowstone Biosciences and Resolution Therapeutics. He was closely involved in the foundation of both companies, including their strategic and operational set-up, through hands-on membership of their founding leadership teams. Previously, Gonzalo was a Project Leader at Boston Consulting Group w…
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Position
Board member
Qualification
PhD
Gwenaelle Pemberton

Gwenaelle Pemberton

Gwenaelle is a Regulatory Advisor to Syncona Investment Management Ltd. Gwenaelle is a senior regulatory leader with over 30 years’ experience in global regulatory strategy in biopharma. Most recently, Gwenaelle was Vice President International Regulatory Affairs at Gilead, leading the International Regulatory Group which was responsible for regulatory activities worldwide, excluding the US. Gwena…
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