Since 2012, Syncona has added 18 companies to its portfolio, investing over £900 million in attractive opportunities, such as cell and gene therapy.

Key stats*


Portfolio companies since 2012


Capital deployed since 2012


Programmes progressed to clinical trial since 2012


Gross multiple on invested capital on three companies sold to date


Gross IRR since inception


Gross multiple on invested capital


Syncona Partners was co-founded in 2012 by our CEO, Martin Murphy, and the Wellcome Trust, a charitable foundation based on healthcare research. Syncona was set up to take a long-term view to building globally competitive life science businesses leveraging the UK/EU scientific research base. 

Between 2012 and 2016, we added eight life sciences businesses to the portfolio, seeking to develop treatments for patients in areas of high level of unmet need.

In 2016, Syncona merged with the Battle Against Cancer Investment Trust (BACIT), becoming a FTSE 250 healthcare company and expanding its permanent capital base.


Syncona added a further four companies to its portfolio, investing across innovative new fields of medicine.

In 2017, Syncona portfolio company, Blue Earth Diagnostics, launched its first marketed commercial product, Axumin, going on to diagnose over 50,000 patients during Syncona's ownership. In 2017-18, two other portfolio companies, Nightstar and Autolus listed on NASDAQ.


Since 2019, Syncona has added a further five companies to its portfolio, listed two companies on NASDAQ (Freeline and Achilles), merged two companies (Gyroscope and Orbit) and sold three portfolio companies. Nightstar was acquired by Biogen for $877 million in March 2019, delivering a 4.5x return on Syncona’s original investment, Blue Earth Diagnostics was sold to Bracco Imaging in June 2019 to deliver a 10x return, and Gyroscope was sold to Novartis in a transaction worth up to $1.5 billion, delivering up front proceeds of £326 million to Syncona. 

*Unless stated all financials at 30 June 2022